Thy-1(+) Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis

Cancer-associated fibroblasts (CAFs) regulate diverse intratumoral biological programs and can promote or inhibit tumorigenesis, but those CAF populations that negatively impact the clinical outcome of lung cancer patients have not been fully elucidated. Because Thy-1 (CD90) marks CAFs that promote...

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Foilsithe in:Sci Rep
Main Authors: Schliekelman, Mark J., Creighton, Chad J., Baird, Brandi N., Chen, Yulong, Banerjee, Priyam, Bota-Rabassedas, Neus, Ahn, Young-Ho, Roybal, Jonathon D., Chen, Fengju, Zhang, Yiqun, Mishra, Dhruva K., Kim, Min P., Liu, Xin, Mino, Barbara, Villalobos, Pamela, Rodriguez-Canales, Jaime, Behrens, Carmen, Wistuba, Ignacio I., Hanash, Samir M., Kurie, Jonathan M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527099/
https://ncbi.nlm.nih.gov/pubmed/28744021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06922-5
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