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Effect of Preventive and Curative Fingolimod Treatment Regimens on Microglia Activation and Disease Progression in a Rat Model of Multiple Sclerosis

Fingolimod was the first oral drug approved for multiple sclerosis treatment. Its principal mechanism of action is blocking of lymphocyte trafficking. In addition, recent studies have shown its capability to diminish microglia activation. The effect of preventive and curative fingolimod treatment on...

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Publicado en:J Neuroimmune Pharmacol
Main Authors: Vállez García, David, Doorduin, Janine, de Paula Faria, Daniele, Dierckx, Rudi A. J. O., de Vries, Erik F. J.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527053/
https://ncbi.nlm.nih.gov/pubmed/28361437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-017-9741-x
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