Evaluation of [(11)C]CB184 for imaging and quantification of TSPO overexpression in a rat model of herpes encephalitis

PURPOSE: Evaluation of translocator protein (TSPO) overexpression is considered an attractive research tool for monitoring neuroinflammation in several neurological and psychiatric disorders. [(11)C]PK11195 PET imaging has been widely used for this purpose. However, it has a low sensitivity and a po...

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Опубликовано в: :Eur J Nucl Med Mol Imaging
Главные авторы: Vállez Garcia, David, de Vries, Erik F. J., Toyohara, Jun, Ishiwata, Kiichi, Hatano, Kentaro, Dierckx, Rudi A. J. O., Doorduin, Janine
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2015
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424274/
https://ncbi.nlm.nih.gov/pubmed/25771904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3021-x
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