Radiosynthesis and in vivo evaluation of two imidazopyridineacetamides, [(11)C]CB184 and [(11)C]CB190, as a PET tracer for 18 kDa translocator protein: direct comparison with [(11)C](R)-PK11195

OBJECTIVE: We report synthesis of two carbon-11 labeled imidazopyridines TSPO ligands, [(11)C]CB184 and [(11)C]CB190, for PET imaging of inflammatory process along with neurodegeneration, ischemia or brain tumor. Biodistribution of these compounds was compared with that of [(11)C]CB148 and [(11)C](R...

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Detalhes bibliográficos
Publicado no:Ann Nucl Med
Main Authors: Hatano, Kentaro, Sekimata, Katsuhiko, Yamada, Takashi, Abe, Junichiro, Ito, Kengo, Ogawa, Mikako, Magata, Yasuhiro, Toyohara, Jun, Ishiwata, Kiichi, Biggio, Giovanni, Serra, Mariangela, Laquintana, Valentino, Denora, Nunzio, Latrofa, Andrea, Trapani, Giuseppe, Liso, Gaetano, Suzuki, Hiromi, Sawada, Makoto, Nomura, Masahiko, Toyama, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835529/
https://ncbi.nlm.nih.gov/pubmed/25616581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12149-015-0948-8
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