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Determination of Seminal Concentration of Fingolimod and Fingolimod‐Phosphate in Multiple Sclerosis Patients Receiving Chronic Treatment With Fingolimod

The safety profile of fingolimod 0.5 mg, approved therapy for relapsing multiple sclerosis, is well established in clinical and real‐world studies. As fingolimod is teratogenic in rats, it was considered important to assess the concentrations of fingolimod and its active metabolite, fingolimod‐phosp...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: David, Olivier J., Berwick, Amy, Pezous, Nicole, Lang, Michael, Tiel‐Wilck, Klaus, Ziemssen, Tjalf, Li, Peng, Hara, Hisanori, Schmouder, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814852/
https://ncbi.nlm.nih.gov/pubmed/29266794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.424
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