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Activation of Mouse Tcrb: Uncoupling RUNX1 Function from its Cooperative Binding with ETS1()
T lineage commitment requires the coordination of key transcription factors (TFs) in multi-potent progenitors (MPP) that transition them away from other lineages and cement T cell identity. Two important TFs for the MPP to T lineage transition are RUNX1 and ETS1, which bind cooperatively to composit...
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| Udgivet i: | J Immunol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526733/ https://ncbi.nlm.nih.gov/pubmed/28637900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700146 |
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