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Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element
Gene regulation relies on dynamic changes in three-dimensional chromatin conformation, which are shaped by composite regulatory and architectural elements. However, mechanisms that govern such conformational switches within chromosomal domains remain unknown. We identify a novel mechanism by which c...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291525/ https://ncbi.nlm.nih.gov/pubmed/25512470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141479 |
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