Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element

Gene regulation relies on dynamic changes in three-dimensional chromatin conformation, which are shaped by composite regulatory and architectural elements. However, mechanisms that govern such conformational switches within chromosomal domains remain unknown. We identify a novel mechanism by which c...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Majumder, Kinjal, Koues, Olivia I., Chan, Elizabeth A.W., Kyle, Katherine E., Horowitz, Julie E., Yang-Iott, Katherine, Bassing, Craig H., Taniuchi, Ichiro, Krangel, Michael S., Oltz, Eugene M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291525/
https://ncbi.nlm.nih.gov/pubmed/25512470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141479
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker