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Activation of Mouse Tcrb: Uncoupling RUNX1 Function from its Cooperative Binding with ETS1()

T lineage commitment requires the coordination of key transcription factors (TFs) in multi-potent progenitors (MPP) that transition them away from other lineages and cement T cell identity. Two important TFs for the MPP to T lineage transition are RUNX1 and ETS1, which bind cooperatively to composit...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Zhao, Jiang-yang, Osipovich, Oleg, Koues, Olivia I., Majumder, Kinjal, Oltz, Eugene M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526733/
https://ncbi.nlm.nih.gov/pubmed/28637900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700146
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