Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense

Successful host defense against pathogens requires innate immune recognition of the correct pathogen associated molecular patterns (PAMPs) by pathogen recognition receptors (PRRs) to trigger the appropriate gene program tailored to the pathogen. While many PRR pathways contribute to the innate immun...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Scumpia, Philip O., Botten, Giovanni A., Norman, Joshua S., Kelly-Scumpia, Kindra M., Spreafico, Roberto, Ruccia, Amber R., Purbey, Prabhat K., Thomas, Brandon J., Modlin, Robert L., Smale, Stephen T.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526579/
https://ncbi.nlm.nih.gov/pubmed/28704551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006496
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