Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense

Successful host defense against pathogens requires innate immune recognition of the correct pathogen associated molecular patterns (PAMPs) by pathogen recognition receptors (PRRs) to trigger the appropriate gene program tailored to the pathogen. While many PRR pathways contribute to the innate immun...

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Vydáno v:PLoS Pathog
Hlavní autoři: Scumpia, Philip O., Botten, Giovanni A., Norman, Joshua S., Kelly-Scumpia, Kindra M., Spreafico, Roberto, Ruccia, Amber R., Purbey, Prabhat K., Thomas, Brandon J., Modlin, Robert L., Smale, Stephen T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526579/
https://ncbi.nlm.nih.gov/pubmed/28704551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006496
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