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B cells and type 1 diabetes …in mice and men
Nearly 70% of newly produced B cells express autoreactive antigen receptors and must be silenced to prevent autoimmunity. Failure of silencing mechanisms is apparent in type 1 diabetes (T1D), where islet antigen-specific B cells appear critical for development of disease. Evidence for a B cell role...
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| Publicado no: | Immunol Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526342/ https://ncbi.nlm.nih.gov/pubmed/24472603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2014.01.010 |
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