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Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori

BACKGROUND: The serine protease HtrA is an important factor for regulating stress responses and protein quality control in bacteria. In recent studies, we have demonstrated that the gastric pathogen Helicobacter pylori can secrete HtrA into the extracellular environment, where it cleaves-off the ect...

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Publicat a:Gut Pathog
Autors principals: Harrer, Aileen, Boehm, Manja, Backert, Steffen, Tegtmeyer, Nicole
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526239/
https://ncbi.nlm.nih.gov/pubmed/28770008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13099-017-0189-6
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