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Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori

BACKGROUND: The serine protease HtrA is an important factor for regulating stress responses and protein quality control in bacteria. In recent studies, we have demonstrated that the gastric pathogen Helicobacter pylori can secrete HtrA into the extracellular environment, where it cleaves-off the ect...

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Détails bibliographiques
Publié dans:Gut Pathog
Auteurs principaux: Harrer, Aileen, Boehm, Manja, Backert, Steffen, Tegtmeyer, Nicole
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526239/
https://ncbi.nlm.nih.gov/pubmed/28770008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13099-017-0189-6
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