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CD4+ T cells from SLE patients respond poorly to exogenous IL-2
OBJECTIVE: Imbalanced cytokine production by T cells characterizes both patients with SLE and lupus-prone mice and contributes to immune dysregulation. In this study, we further characterize in detail the production of IL-2, IFNγ, IL-4 and IL-17A by CD4+ subsets in healthy subjects and SLE patients...
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526072/ https://ncbi.nlm.nih.gov/pubmed/27992687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40014 |
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