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CD4+ T cells from SLE patients respond poorly to exogenous IL-2

OBJECTIVE: Imbalanced cytokine production by T cells characterizes both patients with SLE and lupus-prone mice and contributes to immune dysregulation. In this study, we further characterize in detail the production of IL-2, IFNγ, IL-4 and IL-17A by CD4+ subsets in healthy subjects and SLE patients...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Arthritis Rheumatol
Päätekijät: Comte, Denis, Karampetsou, Maria P., Kis-Toth, Katalin, Yoshida, Nobuya, Bradley, Sean J., Kyttaris, Vasileios C., Tsokos, George C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526072/
https://ncbi.nlm.nih.gov/pubmed/27992687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40014
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