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Decreased SAP expression in T cells from patients with SLE contributes to early signaling abnormalities and reduced IL-2 production

T cells from patients with systemic lupus erythematosus (SLE) display a number of functions including increased early signaling events following engagement of the T cell receptor (TCR). Signaling lymphocytic activation molecule family (SLAMF) cell surface receptors and the X-chromosome-defined signa...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Karampetsou, Maria P., Comte, Denis, Kis-Toth, Katalin, Terhorst, Cox, Kyttaris, Vasileios C., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893906/
https://ncbi.nlm.nih.gov/pubmed/27183584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501523
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