LncRNA MEG3 Downregulation Mediated by DNMT3b Contributes to Nickel Malignant Transformation of Human Bronchial Epithelial Cells via Modulating PHLPP1 Transcription and HIF-1α Translation

Long noncoding RNAs (lncRNAs) are emerging as key players in various fundamental cellular biological processes, and many of them are likely to have functional roles in tumorigenesis. Maternally expressed gene 3 (MEG3) is an imprinted gene located at 14q32 that encodes an lncRNA, and the decreased ME...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Zhou, Chengfan, Huang, Chao, Wang, Jingjing, Huang, Haishan, Li, Jingxia, Xie, Qipeng, Liu, Yu, Zhu, Junlan, Li, Yang, Zhang, Dongyun, Zhu, Qixing, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525547/
https://ncbi.nlm.nih.gov/pubmed/28263966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.14
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