Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents

RecQ family DNA helicases function in the maintenance of genome stability. Mice deficient in RecQL5, one of five RecQ helicases, show a cancer predisposition phenotype, suggesting that RecQL5 plays a tumor suppressor role. RecQL5 interacts with Rad51, a key factor in homologous recombination (HR), a...

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Detaylı Bibliyografya
Yayımlandı:Biochim Biophys Acta
Asıl Yazarlar: Hosono, Yoshifumi, Abe, Takuya, Ishiai, Masamichi, Islam, M. Nurul, Arakawa, Hiroshi, Wang, Weidong, Takeda, Shunichi, Ishii, Yutaka, Takata, Minoru, Seki, Masayuki, Enomoto, Takemi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525539/
https://ncbi.nlm.nih.gov/pubmed/24418621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.01.005
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