Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents

RecQ family DNA helicases function in the maintenance of genome stability. Mice deficient in RecQL5, one of five RecQ helicases, show a cancer predisposition phenotype, suggesting that RecQL5 plays a tumor suppressor role. RecQL5 interacts with Rad51, a key factor in homologous recombination (HR), a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochim Biophys Acta
Prif Awduron: Hosono, Yoshifumi, Abe, Takuya, Ishiai, Masamichi, Islam, M. Nurul, Arakawa, Hiroshi, Wang, Weidong, Takeda, Shunichi, Ishii, Yutaka, Takata, Minoru, Seki, Masayuki, Enomoto, Takemi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525539/
https://ncbi.nlm.nih.gov/pubmed/24418621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.01.005
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