Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents

RecQ family DNA helicases function in the maintenance of genome stability. Mice deficient in RecQL5, one of five RecQ helicases, show a cancer predisposition phenotype, suggesting that RecQL5 plays a tumor suppressor role. RecQL5 interacts with Rad51, a key factor in homologous recombination (HR), a...

Full description

Saved in:
Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Hosono, Yoshifumi, Abe, Takuya, Ishiai, Masamichi, Islam, M. Nurul, Arakawa, Hiroshi, Wang, Weidong, Takeda, Shunichi, Ishii, Yutaka, Takata, Minoru, Seki, Masayuki, Enomoto, Takemi
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525539/
https://ncbi.nlm.nih.gov/pubmed/24418621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.01.005
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items