Osteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots

Cells of the osteoblast lineage are increasingly identified as participants in whole-body metabolism by primarily targeting pancreatic insulin secretion or consuming energy. Osteocytes, the most abundant bone cells, secrete a Wnt-signaling inhibitor called sclerostin. Here we examined three mouse mo...

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發表在:J Bone Miner Res
Main Authors: Fulzele, Keertik, Lai, Forest, Dedic, Christopher, Saini, Vaibhav, Uda, Yuhei, Shi, Chao, Tuck, Padrig, Aronson, Jenna L, Liu, Xiaolong, Spatz, Jordan M, Wein, Marc N, Pajevic, Paola Divieti
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525330/
https://ncbi.nlm.nih.gov/pubmed/27653320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3001
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