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Nanopore long-read RNAseq reveals widespread transcriptional variation among the surface receptors of individual B cells
Understanding gene regulation and function requires a genome-wide method capable of capturing both gene expression levels and isoform diversity at the single-cell level. Short-read RNAseq is limited in its ability to resolve complex isoforms because it fails to sequence full-length cDNA copies of RN...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5524981/ https://ncbi.nlm.nih.gov/pubmed/28722025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms16027 |
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