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Improved data analysis for the MinION nanopore sequencer
The Oxford Nanopore MinION sequences individual DNA molecules using an array of pores that read nucleotide identities based on ionic current steps. We evaluated and optimized MinION performance using M13 genomic dsDNA. Using expectation-maximization (EM) we obtained robust maximum likelihood (ML) es...
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| Publicat a: | Nat Methods |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907500/ https://ncbi.nlm.nih.gov/pubmed/25686389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3290 |
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