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Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress

Alantolactone (ALT), a sesquiterpene lactone component of Inula helenium, has been reported to exert anticancer activity in various cancers. However, the cellular targets and underlying mechanism of anticancer activity of ALT in various cancers including lung cancer has not been fully defined. In th...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Maryam, Amara, Mehmood, Tahir, Zhang, He, Li, Yongming, Khan, Muhammad, Ma, Tonghui
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524969/
https://ncbi.nlm.nih.gov/pubmed/28740138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06535-y
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