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Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase
Intestinal epithelial barrier properties are maintained by a junctional complex consisting of tight junctions (TJ), adherens junctions (AJ) and desmosomes. Desmoglein 2 (Dsg2), an adhesion molecule of desmosomes and the only Dsg isoform expressed in enterocytes, is required for epithelial barrier pr...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5524837/ https://ncbi.nlm.nih.gov/pubmed/28740231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06713-y |
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