Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Intestinal epithelial barrier properties are maintained by a junctional complex consisting of tight junctions (TJ), adherens junctions (AJ) and desmosomes. Desmoglein 2 (Dsg2), an adhesion molecule of desmosomes and the only Dsg isoform expressed in enterocytes, is required for epithelial barrier pr...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Ungewiß, Hanna, Vielmuth, Franziska, Suzuki, Shintaro T., Maiser, Andreas, Harz, Hartmann, Leonhardt, Heinrich, Kugelmann, Daniela, Schlegel, Nicolas, Waschke, Jens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524837/
https://ncbi.nlm.nih.gov/pubmed/28740231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06713-y
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