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Desmosomal Hyperadhesion Is Accompanied with Enhanced Binding Strength of Desmoglein 3 Molecules

Intercellular adhesion of keratinocytes depends critically on desmosomes that, during maturation, acquire a hyperadhesive and thus Ca(2+) independent state. Here, we investigated the roles of desmoglein (Dsg) 3 and plakophilins (Pkps) in hyperadhesion. Atomic force microscopy single molecule force m...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Fuchs, Michael, Sigmund, Anna Magdalena, Waschke, Jens, Vielmuth, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642361/
https://ncbi.nlm.nih.gov/pubmed/33031738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.09.008
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