A Proposal for a Structural Model of the Feline Calicivirus Protease Bound to the Substrate Peptide under Physiological Conditions

Feline calicivirus (FCV) protease functions to cleave viral precursor proteins during productive infection. Previous studies have mapped a protease-coding region and six cleavage sites in viral precursor proteins. However, how the FCV protease interacts with its substrates remains unknown. To gain i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Yokoyama, Masaru, Oka, Tomoichiro, Takagi, Hirotaka, Kojima, Hirotatsu, Okabe, Takayoshi, Nagano, Tetsuo, Tohya, Yukinobu, Sato, Hironori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524728/
https://ncbi.nlm.nih.gov/pubmed/28790989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01383
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