A Proposal for a Structural Model of the Feline Calicivirus Protease Bound to the Substrate Peptide under Physiological Conditions

Feline calicivirus (FCV) protease functions to cleave viral precursor proteins during productive infection. Previous studies have mapped a protease-coding region and six cleavage sites in viral precursor proteins. However, how the FCV protease interacts with its substrates remains unknown. To gain i...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Yokoyama, Masaru, Oka, Tomoichiro, Takagi, Hirotaka, Kojima, Hirotatsu, Okabe, Takayoshi, Nagano, Tetsuo, Tohya, Yukinobu, Sato, Hironori
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524728/
https://ncbi.nlm.nih.gov/pubmed/28790989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01383
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