Structural Basis for Specific Recognition of Substrates by Sapovirus Protease

Sapovirus (SaV) protease catalyzes cleavage of the peptide bonds at six sites of a viral polyprotein for the viral replication and maturation. However, the mechanisms by which the protease recognizes the distinct sequences of the six cleavage sites remain poorly understood. Here we examined this iss...

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Bibliographic Details
Main Authors: Yokoyama, Masaru, Oka, Tomoichiro, Kojima, Hirotatsu, Nagano, Tetsuo, Okabe, Takayoshi, Katayama, Kazuhiko, Wakita, Takaji, Kanda, Tadahito, Sato, Hironori
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433708/
https://ncbi.nlm.nih.gov/pubmed/22973264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2012.00312
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