Microglial depletion and activation: A [(11)C]PBR28 PET study in nonhuman primates

BACKGROUND: The 18-kDa translocator protein (TSPO) is an important target for assessing neuroimmune function in brain with positron-emission tomography (PET) imaging. The goal of this work was to assess two [(11)C]PBR28 imaging paradigms for measuring dynamic microglia changes in Macaca mulatta. MET...

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Foilsithe in:EJNMMI Res
Main Authors: Hillmer, Ansel T., Holden, Daniel, Fowles, Krista, Nabulsi, Nabeel, West, Brian L., Carson, Richard E., Cosgrove, Kelly P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Berlin Heidelberg 2017
Ábhair:
Preliminary Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524658/
https://ncbi.nlm.nih.gov/pubmed/28741281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-017-0305-0
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