Endotoxin-Induced Systemic Inflammation Activates Microglia: [(11)C]PBR28 Positron Emission Tomography in Nonhuman Primates

Microglia play an essential role in many brain diseases. Microglia are activated by local tissue damage or inflammation, but systemic inflammation can also activate microglia. An important clinical question is whether the effects of systemic inflammation on microglia mediates the deleterious effects...

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Main Authors: Hannestad, Jonas, Gallezot, Jean-Dominique, Schafbauer, Thomas, Lim, Keunpoong, Kloczynski, Tracy, Morris, Evan D., Carson, Richard E, Ding, Yu-Shin, Cosgrove, Kelly
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699786/
https://ncbi.nlm.nih.gov/pubmed/22776451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2012.06.055
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