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An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation

The latent EBV nuclear antigen 3C (EBNA3C) is required for transformation of primary human B lymphocytes. Most mature B-cell malignancies originate from malignant transformation of germinal center (GC) B-cells. The GC reaction appears to have a role in malignant transformation, in which a major play...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Pei, Yonggang, Banerjee, Shuvomoy, Jha, Hem Chandra, Sun, Zhiguo, Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524291/
https://ncbi.nlm.nih.gov/pubmed/28738086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006500
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