The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8

Epstein-Barr virus (EBV) is linked to a broad spectrum of B-cell malignancies. EBV nuclear antigen 3C (EBNA3C) is an encoded latent antigen required for growth transformation of primary human B-lymphocytes. Interferon regulatory factor 4 (IRF4) and 8 (IRF8) are transcription factors of the IRF famil...

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Detalhes bibliográficos
Main Authors: Banerjee, Shuvomoy, Lu, Jie, Cai, Qiliang, Saha, Abhik, Jha, Hem Chandra, Dzeng, Richard Kuo, Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642079/
https://ncbi.nlm.nih.gov/pubmed/23658517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003314
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