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EBNA3C Augments Pim-1 Mediated Phosphorylation and Degradation of p21 to Promote B-Cell Proliferation

Epstein–Barr virus (EBV), a ubiquitous human herpesvirus, can latently infect the human population. EBV is associated with several types of malignancies originating from lymphoid and epithelial cell types. EBV latent antigen 3C (EBNA3C) is essential for EBV-induced immortalization of B-cells. The Mo...

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Detalhes bibliográficos
Main Authors: Banerjee, Shuvomoy, Lu, Jie, Cai, Qiliang, Sun, Zhiguo, Jha, Hem Chandra, Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133388/
https://ncbi.nlm.nih.gov/pubmed/25121590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004304
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