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Evaluation of [(18)F]-ATRi as PET tracer for in vivo imaging of ATR in mouse models of brain cancer()

RATIONALE: Ataxia telangiectasia and Rad3-related (ATR) threonine serine kinase is one of the key elements in orchestrating the DNA damage response (DDR). As such, inhibition of ATR can amplify the effects of chemo- and radiation-therapy, and several ATR inhibitors (ATRi) have already undergone clin...

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Bibliografische gegevens
Gepubliceerd in:Nucl Med Biol
Hoofdauteurs: Carlucci, Giuseppe, Carney, Brandon, Sadique, Ahmad, Vansteene, Axel, Tang, Jun, Reiner, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524211/
https://ncbi.nlm.nih.gov/pubmed/28157626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2017.01.002
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