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Ionizing Radiation Sensitizes Breast Cancer Cells to Bcl-2 Inhibitor, ABT-737, through Regulating Mcl-1

Breast-conserving surgery followed by radiation therapy has become the standard of care for early stage breast cancer. However, there are some patients that develop a local failure. We have previously shown that Bcl-2 overexpression was associated with an increased risk of local recurrence in patien...

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Publicat a:Radiat Res
Autors principals: Wu, Hao, Schiff, Devora S., Lin, Yong, Neboori, Hanmanth J. R., Goyal, Sharad, Feng, Zhaohui, Haffty, Bruce G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523983/
https://ncbi.nlm.nih.gov/pubmed/25409124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13856.1
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