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A-1210477, a selective MCL-1 inhibitor, overcomes ABT-737 resistance in AML

Acute myeloid leukemia (AML) is one of the most common hematological malignancies. It is difficult to treat since it easily develops resistance to therapeutic drugs. Myeloid cell leukemia 1 (MCL-1), BCL-2 and BCL-XL, which belong to the anti-apoptotic group of proteins in the BCL-2 family, are overe...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Wang, Qing, Hao, Siguo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781566/
https://ncbi.nlm.nih.gov/pubmed/31612056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10891
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