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A-1210477, a selective MCL-1 inhibitor, overcomes ABT-737 resistance in AML

Acute myeloid leukemia (AML) is one of the most common hematological malignancies. It is difficult to treat since it easily develops resistance to therapeutic drugs. Myeloid cell leukemia 1 (MCL-1), BCL-2 and BCL-XL, which belong to the anti-apoptotic group of proteins in the BCL-2 family, are overe...

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Bibliografski detalji
Izdano u:Oncol Lett
Glavni autori: Wang, Qing, Hao, Siguo
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781566/
https://ncbi.nlm.nih.gov/pubmed/31612056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10891
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