Genetics of pleiotropic effects of dexamethasone

OBJECTIVES: Glucocorticoids such as dexamethasone have pleiotropic effects, including desired antileukemic, anti-inflammatory or immunosuppressive effects, and undesired metabolic or toxic effects. The most serious adverse effects of dexamethasone among patients with acute lymphoblastic leukemia (AL...

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Detalhes bibliográficos
Publicado no:Pharmacogenet Genomics
Main Authors: Ramsey, Laura B., Pounds, Stan, Cheng, Cheng, Cao, Xueyuan, Yang, Wenjian, Smith, Colton, Karol, Seth E., Liu, Chengcheng, Panetta, John C., Inaba, Hiroto, Rubnitz, Jeffrey E., Metzger, Monika L., Ribeiro, Raul C., Sandlund, John T., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523978/
https://ncbi.nlm.nih.gov/pubmed/28628558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000293
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