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Nontelomeric Role for Rap1 in Regulating Metabolism and Protecting against Obesity

The mammalian telomere-binding protein Rap1 was recently found to have additional nontelomeric functions, acting as a transcriptional cofactor and a regulator of the NF-κB pathway. Here, we assess the effect of disrupting mouse Rap1 in vivo and report on its unanticipated role in metabolic regulatio...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Yeung, Frank, Ramírez, Cristina M., Mateos-Gomez, Pedro A., Pinzaru, Alexandra, Ceccarini, Giovanni, Kabir, Shaheen, Fernández-Hernando, Carlos, Sfeir, Agnel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523811/
https://ncbi.nlm.nih.gov/pubmed/23791522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.05.032
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