Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking‐Dependent and Crosslinking‐Independent Functions

BACKGROUND: The structural elements of the vascular wall, namely, extracellular matrix and smooth muscle cells (SMCs), contribute to the overall stiffness of the vessel. In this study, we examined the crosslinking‐dependent and crosslinking‐independent roles of tissue transglutaminase (TG2) in vascu...

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Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Steppan, Jochen, Bergman, Yehudit, Viegas, Kayla, Armstrong, Dinani, Tan, Siqi, Wang, Huilei, Melucci, Sean, Hori, Daijiro, Park, Sung Yong, Barreto, Sebastian F., Isak, Abraham, Jandu, Sandeep, Flavahan, Nicholas, Butlin, Mark, An, Steven S., Avolio, Alberto, Berkowitz, Dan E., Halushka, Marc K., Santhanam, Lakshmi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523743/
https://ncbi.nlm.nih.gov/pubmed/28159817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004161
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