Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice

Nitric oxide (NO) can modulate arterial stiffness by regulating both functional and structural changes in the arterial wall. Tissue transglutaminase (TG2) has been shown to contribute to increased central aortic stiffness by catalyzing the cross-linking of matrix proteins. NO S-nitrosylates and cons...

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Detalhes bibliográficos
Main Authors: Jung, Sung Mee, Jandu, Simran, Steppan, Jochen, Belkin, Alexey, An, Steven S., Pak, Alina, Choi, Eric Y., Nyhan, Daniel, Butlin, Mark, Viegas, Kayla, Avolio, Alberto, Berkowitz, Dan E., Santhanam, Lakshmi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761342/
https://ncbi.nlm.nih.gov/pubmed/23873798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00103.2013
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