Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking‐Dependent and Crosslinking‐Independent Functions

BACKGROUND: The structural elements of the vascular wall, namely, extracellular matrix and smooth muscle cells (SMCs), contribute to the overall stiffness of the vessel. In this study, we examined the crosslinking‐dependent and crosslinking‐independent roles of tissue transglutaminase (TG2) in vascu...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Steppan, Jochen, Bergman, Yehudit, Viegas, Kayla, Armstrong, Dinani, Tan, Siqi, Wang, Huilei, Melucci, Sean, Hori, Daijiro, Park, Sung Yong, Barreto, Sebastian F., Isak, Abraham, Jandu, Sandeep, Flavahan, Nicholas, Butlin, Mark, An, Steven S., Avolio, Alberto, Berkowitz, Dan E., Halushka, Marc K., Santhanam, Lakshmi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523743/
https://ncbi.nlm.nih.gov/pubmed/28159817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004161
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