Autophagic degradation of FOXO3a represses the expression of PUMA to block cell apoptosis in cisplatin-resistant osteosarcoma cells

Autophagy and apoptosis are the two major modes of cell death, and autophagy usually inhibits apoptosis. The current understanding has shown that there is a complex crosstalk between the components of these two pathways. Here, we describe a transcriptional mechanism that links autophagy to apoptosis...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Jiang, Kaibiao, Zhang, Caiguo, Yu, Bo, Chen, Bin, Liu, Zude, Hou, Canglong, Wang, Fei, Shen, Hongxing, Chen, Zhi
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523024/
https://ncbi.nlm.nih.gov/pubmed/28744393
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