Modulation of Endothelial BMPR2 Activity by VEGFR3 in Pulmonary Arterial Hypertension

BACKGROUND: Bone Morphogenetic Protein (BMP) signaling has multiple roles in the development and function of the blood vessels. In humans, mutations in BMP type 2 receptors (BMPR2), a key component of BMP signaling, have been identified in the majority of patients with familial pulmonary arterial hy...

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Publicado en:Circulation
Main Authors: Hwangbo, Cheol, Lee, Heon-Woo, Kang, Hyeseon, Ju, Hyekyung, Wiley, David S., Papangeli, Irinna, Han, Jinah, Kim, Jun-Dae, Dunworth, William P., Hu, Xiaoyue, Lee, Seyoung, El-Hely, Omar, Sofer, Avraham, Pak, Boryeong, Peterson, Laura, Comhair, Suzy, Hwang, Eun Mi, Park, Jae-Yong, Thomas, Jean-Leon, Bautch, Victoria L., Erzurum, Serpil C., Chun, Hyung J., Jin, Suk-Won
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523010/
https://ncbi.nlm.nih.gov/pubmed/28356442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.025390
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