Micro- and Nano-vesicles from First Trimester Human Placentae Carry Flt-1 and Levels Are Increased in Severe Preeclampsia

BACKGROUND/OBJECTIVES: Preeclampsia is a life-threatening hypertensive disease affecting 3–5% of pregnancies. While the pathogenesis of preeclampsia remains unclear, it is known that placenta-derived factors trigger the disease by activating maternal endothelial cells prior to the onset of clinical...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autoři: Tong, Mancy, Chen, Qi, James, Joanna L., Stone, Peter R., Chamley, Lawrence W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522845/
https://ncbi.nlm.nih.gov/pubmed/28790977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00174
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