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Aggregated transthyretin is specifically packaged into placental nano-vesicles in preeclampsia
In preeclampsia, the serum levels of transthyretin, a carrier protein for thyroxine, are elevated. Transthyretin isolated from preeclamptic serum is also aggregated and can induce preeclampsia-like symptoms in pregnant IL10(−/−) mice. Using western blotting, immunofluorescence, ELISA and qRT-PCR, we...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5532246/ https://ncbi.nlm.nih.gov/pubmed/28751735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07017-x |
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