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Antiphospholipid antibodies increase the levels of mitochondrial DNA in placental extracellular vesicles: Alarmin-g for preeclampsia

The pathogenesis of preeclampsia remains unclear but placental factors are known to play a crucial role causing maternal endothelial cell dysfunction. One potential factor is placental micro- and nano- vesicles. Antiphospholipid antibodies (aPL) increase the risk of preeclampsia ten-fold, in part by...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tong, Mancy, Johansson, Caroline, Xiao, Fengyi, Stone, Peter R., James, Joanna L., Chen, Qi, Cree, Lynsey M., Chamley, Lawrence W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707355/
https://ncbi.nlm.nih.gov/pubmed/29185455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16448-5
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