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Direct visualization of supercoiled DNA molecules in solution.

The shape of supercoiled DNA molecules in solution is directly visualized by cryo-electron microscopy of vitrified samples. We observe that: (i) supercoiled DNA molecules in solution adopt an interwound rather than a toroidal form, (ii) the diameter of the interwound superhelix changes from about 12...

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Bibliografiske detaljer
Main Authors: Adrian, M, ten Heggeler-Bordier, B, Wahli, W, Stasiak, A Z, Stasiak, A, Dubochet, J
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC552252/
https://ncbi.nlm.nih.gov/pubmed/2265618
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