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Direct visualization of supercoiled DNA molecules in solution.

The shape of supercoiled DNA molecules in solution is directly visualized by cryo-electron microscopy of vitrified samples. We observe that: (i) supercoiled DNA molecules in solution adopt an interwound rather than a toroidal form, (ii) the diameter of the interwound superhelix changes from about 12...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Adrian, M, ten Heggeler-Bordier, B, Wahli, W, Stasiak, A Z, Stasiak, A, Dubochet, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552252/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2265618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07907.x
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